IMBY Calm & Chill Supplement

Ashwagandha is an adaptogenic root traditionally used to support resilience during stress. In dogs, a randomized, double-blind, placebo-controlled study evaluated a standardized ashwagandha root extract in dogs experiencing stress and anxiety, supporting its use as a calming, daily-support botanical. It is best positioned for mild to moderate stress support alongside training routines and predictable daily structure. ScienceDirect

Passionflower (Passiflora incarnata) is a botanical ingredient traditionally used for its calming properties. It contains flavonoids and other plant compounds that have been studied for their interaction with GABA-related pathways, which are involved in relaxation and nervous system balance.

These pathways play a role in regulating excitability in the brain and supporting a more relaxed state. As a result, passionflower is often associated with helping animals cope with stress and maintain calm behavior.

Because of its gentle calming properties, passionflower is commonly included in nutritional formulations aimed at supporting relaxation and emotional balance in dogs during stressful situations (Verhelst, 2025).

Magnesium glycinate is a highly bioavailable form of magnesium in which magnesium is bound to the amino acid glycine. This form is well absorbed and gentle on the digestive system, making it suitable for regular use in nutritional formulations.

Magnesium plays an important role in muscle function by helping regulate contraction and relaxation. Adequate magnesium intake supports normal muscle relaxation, which is important for both physical comfort and smooth movement.

In addition, magnesium contributes to normal nervous system function. The presence of glycine, an amino acid involved in inhibitory neurotransmission, further supports a calming effect by helping maintain balanced nerve signaling.

Because of its role in both muscle and nerve function, magnesium glycinate is commonly included in formulations aimed at supporting relaxation, reducing tension, and maintaining overall mobility and comfort in dogs (Boomsma, 2008; Noah, 2021; Wienecke, 2016).

Algal oil is a sustainable, traceable source of omega-3s, naturally rich in DHA and often EPA, and it supports the body’s healthy inflammatory balance. 

• Joint health: Omega-3s help keep the normal inflammatory response in check, which can support more comfortable movement and recovery after exercise. 
• Skin and coat: DHA and EPA support the skin barrier, helping reduce dryness and supporting a softer, shinier coat, especially in animals prone to flaky skin or seasonal itchiness. 
• Lung health: Omega-3s can support respiratory comfort by helping maintain a balanced inflammatory response in the airways, which is relevant for pets that react to dust, pollen, or environmental triggers. 

Because algal oil delivers omega-3s in a consistent way, it is a practical alternative to fish oil for long-term daily support of joints, skin, and respiratory resilience (ScienceDirect). 

Lemon balm (Melissa officinalis) is a botanical herb traditionally used for its calming properties. It contains bioactive compounds such as rosmarinic acid, which have been studied for their interaction with pathways involved in relaxation and stress response.

In addition to its calming effects, lemon balm is also associated with digestive support. The gut and nervous system are closely connected, and maintaining digestive comfort can contribute to overall wellbeing and calm behavior.

Because of its dual role in supporting relaxation and digestive balance, lemon balm is often included in formulations aimed at helping dogs cope with stress while maintaining gastrointestinal comfort (Verhelst, 2025).

Vitamin B12 (cobalamin) is a water-soluble vitamin that plays an essential role in energy metabolism and cellular function. It participates in enzymatic reactions involved in DNA synthesis and the formation of red blood cells, which are important for oxygen transport and overall vitality.

Vitamin B12 works closely together with folate in one-carbon metabolism, a pathway involved in the synthesis van nucleic acids and other essential biological molecules. These processes support cellular growth, tissue maintenance, and overall metabolic balance.

In addition, vitamin B12 contributes to normal nervous system function and is involved in pathways linked to mood regulation. Research shows that low vitamin B12 levels are associated with changes in mood and increased signs of stress-related conditions such as anxiety and depression. Maintaining adequate levels therefore supports overall mental balance and resilience (Todorov et al., 2017 ; Stover, 2004; Curely, 2025).

Vitamin B6 (pyridoxine) is a water-soluble vitamin that plays an essential role in amino acid metabolism and numerous enzymatic reactions in the body. It functions as a cofactor for enzymes involved in the metabolism of proteins, carbohydrates, and fats, supporting overall energy and nutrient utilization.

Vitamin B6 also contributes to the normal function of the nervous system by participating in the synthesis of neurotransmitters such as serotonin and dopamine. These compounds are involved in mood regulation, behavior, and the body’s response to stress, making vitamin B6 relevant in nutritional strategies aimed at supporting calm and balanced behavior.

In addition, vitamin B6 supports immune function and contributes to normal metabolic activity in rapidly renewing tissues such as skin. A well-functioning immune system and healthy skin are important for overall resilience and wellbeing.

Because of its combined role in metabolism, nervous system function, and immune support, vitamin B6 is commonly included in formulations aimed at supporting both emotional balance and overall health in dogs (Curely, 2025).

Peas are widely used in animal nutrition as a plant-based protein and fiber source. Their protein can be highly digestible depending on processing, and peas can also contribute fermentable fiber that supports normal stool quality. Wang et al., 2022

Brewer’s yeast (Saccharomyces cerevisiae) is a functional yeast ingredient naturally rich in nutrients and yeast-derived compounds such as beta-glucans, mannan-oligosaccharides, and fermentation metabolites. These components are studied for their role in supporting digestive health, immune function, and overall wellbeing in dogs.

In canine studies, Saccharomyces cerevisiae products have been shown to positively influence the gut microbiota, including increased beneficial bacteria such as Bifidobacterium, while also supporting immune markers and normal inflammatory balance.

Research in dogs also links Saccharomyces cerevisiae fermentation products to skin and coat support, including effects on skin sebum, antioxidant status, and immune responses. This makes brewer’s yeast especially relevant in formulations aimed at supporting gut health, skin resilience, and coat quality (Jouany et al., 2009; Davenport, 2023; Lin, 2019; Wilson, 2022).

Apple (Malus domestica) is a natural source of pectin, a soluble fiber known for its role in supporting digestive health. Pectin forms a gel-like structure in the gut, which helps regulate intestinal transit and contributes to normal stool consistency.

As a fermentable fiber, pectin serves as a substrate for beneficial gut bacteria. This supports a balanced microbiome, which plays an important role in digestion, nutrient absorption, and overall gut health.

The gut and nervous system are closely connected through the gut–brain axis. Supporting a stable gut environment can therefore contribute to overall wellbeing and a more balanced response to everyday stressors. This makes pectin relevant not only for digestive support but also as part of a broader approach to maintaining calm and comfort in sensitive animals (Wikiera, 2014; Zaitseva, 2020).

Calcium is an essential mineral that plays a key role in maintaining strong bones and overall structural support in the body. A healthy skeletal system is important for movement, stability, and joint function.

Beyond its role in bones, calcium is involved in muscle function and nerve signaling, helping support coordinated movement and normal physical activity.

Calcium also plays a role in normal cellular processes, including those involved in skin renewal and tissue maintenance. These processes contribute to maintaining healthy skin and overall physiological balance (Böswald, 2019; British Journal of Nutrition, 2011; Foods, 2025).

Vitamin B5, also known as pantothenic acid, is a water-soluble vitamin involved in many metabolic processes in the body. It is a key component of coenzyme A, which plays an essential role in the metabolism of carbohydrates, proteins, and fats, supporting normal energy production.

Through its role in metabolism, vitamin B5 contributes to maintaining muscle function and overall physical performance, which is particularly relevant in animals with increased activity levels.

Vitamin B5 also supports the maintenance of healthy skin and contributes to normal cellular renewal in tissues such as the skin and the digestive tract. These processes are important for maintaining skin condition, gut integrity, and overall wellbeing (Kobayashi, 2011).

In addition, pantothenic acid plays a role in maintaining normal physiological balance and supports processes involved in immune function (Curely, 2025).

Vitamin B1 (thiamine) is a water-soluble vitamin involved in carbohydrate metabolism and energy production. It plays a key role in converting nutrients into usable energy, supporting overall vitality.

Thiamine is also important for normal nervous system function, as it supports nerve signaling and cellular communication. Proper nervous system function contributes to overall physiological balance and behaviour.

Because of its role in energy metabolism and nerve function, vitamin B1 contributes to maintaining general health and resilience in both dogs and horses (Curely, 2025).

Vitamin B2 (riboflavin) is a water-soluble vitamin involved in energy metabolism and cellular function. It acts as a cofactor in enzymatic reactions that help convert nutrients into energy.

Riboflavin also plays a role in maintaining healthy skin and supporting normal cellular turnover. These processes are important for preserving skin integrity and overall tissue health.

In addition, vitamin B2 contributes to antioxidant processes in the body, helping maintain cellular balance and supporting overall wellbeing (Curely, 2025).