Smooth & Supple Supplement

Aesculus hippocastanum (horse chestnut) powder contains several plant compounds, with aescin (β-escin) among the most studied. It is used to support microcirculation in small blood vessels and help tissues retain less excess fluid by making tiny vessels less permeable, or less leaky, so less fluid moves into surrounding tissue. By supporting fluid balance and a healthy inflammatory response around tissues, it can also be linked to supporting joint comfort and mobility over time.
Domanski et al., 2016; Wienert, 1997; Sirtori (2001)

MSM (methylsulfonylmethane) is an organic sulfur compound that plays an important role in several physiological processes in the body. Sulfur is a key building block of amino acids and structural proteins such as keratin and collagen, which contribute to the strength and integrity of connective tissues including hooves, joints, skin, and tendons.

Through this structural role, MSM supports tissue quality and resilience, which is relevant for maintaining strong hooves and healthy joints, especially in horses exposed to physical stress or metabolic challenges.

In addition, sulfur is involved in metabolic pathways linked to the body’s antioxidant systems. These pathways support the processing of metabolic by-products and contribute to maintaining normal cellular balance. This makes MSM relevant in nutritional strategies aimed at supporting liver function, digestion, and overall metabolic stability.

Because of its dual role in both structural support and metabolic processes, MSM contributes to maintaining connective tissue health, digestive balance, and overall physiological resilience (Jiao et al., 2025; Marañón et al., 2008; Kalman, 2012).

Meadowsweet (Filipendula ulmaria) is a flowering herb traditionally used in herbal nutrition for its naturally occurring phenolic compounds, including salicylate derivatives and flavonoids. These compounds have been studied for their interaction with pathways involved in maintaining normal inflammatory balance and tissue comfort.

Maintaining healthy circulation is important for supplying nutrients and oxygen to connective tissues such as joints, tendons, and ligaments. Botanical ingredients that support circulation may therefore contribute to maintaining normal joint function and mobility.

Because of its traditional use and bioactive plant compounds, meadowsweet is sometimes included in nutritional formulations aimed at supporting joint comfort and helping maintain healthy circulation in animals with increased physical demands or age-related joint sensitivity. (Farzaneh, 2022)

Turmeric is used to support joint comfort because curcumin and related compounds help maintain a healthy inflammatory response. In dogs with osteoarthritis, controlled studies and veterinary research are emerging, including trials investigating turmeric-derived ingredients for mobility and comfort outcomes. 

Turmeric can also support digestive health by helping maintain a balanced gut environment. Research suggests curcumin may influence the gut microbiome by supporting beneficial bacteria and helping reduce irritation in the intestinal lining, which can be helpful for overall gut resilience. Springer Nature Link, Frontiers, Scazzocchio et al. 2020, Andrews et. al. 2022

Boswellia is used to support mobility and joint comfort in both dogs and horses because its boswellic acids help maintain a balanced inflammatory response, which can support more comfortable movement. 

In dogs: Boswellia has been studied in osteoarthritis supplements, often as part of multi-ingredient formulas. Some randomized controlled trials report improvements in comfort and mobility based on owner observations and veterinary assessments. It is best used alongside a complete joint plan: healthy body weight, appropriate exercise, and veterinary guidance. Barrouin-Melo et al., 2022, Multicenter RCT, 2025 (Frontiers in Veterinary Science) 

In horses:Boswellia is commonly used to support joints and post-exercise comfort, especially in older horses or those in regular training. While horse-specific clinical studies are more limited than in dogs, its traditionaluseand the known activity ofboswellicacids make it a popular supportive botanical formaintainingfree, comfortable movement. As with dogs, it works best when the basics are right: a balancedration, correct training, good hoof care, and a sensible workload. Vita et al., 2023 (Life, MDPI)

Blackcurrantcontainspolyphenols and other plant compounds valued for antioxidant support. In veterinary use, blackcurrant leaf extract has been included in controlled studies evaluating multi-ingredient joint supplements for dogs and cats with osteoarthritis, supporting its positioning for mobility and comfort. As with many botanicals, blackcurrant works best as supportive nutrition rather than a replacement for pain management when needed. dspace.library.uu.nl

Glucosamine is a naturally occurring amino monosaccharide that serves as a building block for glycosaminoglycans and other structural molecules in the body. Glycosaminoglycans are important components of connective tissues such as cartilage and also contribute to the structure of mucosal surfaces throughout the body.

These molecules help maintain the strength, elasticity, and structural integrity of connective tissues. In biological systems, glucosamine participates in pathways that support the synthesis and maintenance of these structural components, which are essential for maintaining normal tissue function.

Glycosaminoglycans and related molecules also contribute to the protective mucosal layers found in the gastrointestinal tract. These layers help maintain barrier integrity and support the interaction between the intestinal lining and the microbiome, which is important for digestive stability and overall physiological balance.

Because of its role as a structural precursor in connective tissues and mucosal systems, glucosamine is often included in nutritional formulations aimed at supporting tissue maintenance, gastrointestinal integrity, and overall physiological resilience. ScienceDirect

Diglycerides are naturally occurring lipid molecules composed of glycerol and two fatty acids. They are intermediate products in fat digestion and are commonly present in dietary fats and oils. In nutrition, they serve as a source of fatty acids that contribute to cellular metabolism and energy supply.

Lipids also play an important role in the absorption of fat-soluble nutrients such as vitamins A, D, and E, which are involved in maintaining connective tissues and joint health. Adequate lipid availability can therefore support the effective uptake of these nutrients in the body.

Because fatty acids contribute to normal cellular structure and metabolic balance, diglycerides are sometimes included in nutritional formulations designed to support joint tissues, connective structures, and overall physiological function in animals. (K. Lanchais, 2020)

Calcium is an essential mineral that plays a key role in maintaining strong bones and overall structural support in the body. A healthy skeletal system is important for movement, stability, and joint function.

Beyond its role in bones, calcium is involved in muscle function and nerve signaling, helping support coordinated movement and normal physical activity.

Calcium also plays a role in normal cellular processes, including those involved in skin renewal and tissue maintenance. These processes contribute to maintaining healthy skin and overall physiological balance (Böswald, 2019; British Journal of Nutrition, 2011; Foods, 2025).